Follicle

A follicle is a small, fluid-filled sac located in the ovaries. Each follicle contains an immature egg (oocyte) and plays a central role in the menstrual cycle, ovulation, and fertility.


🧬 Function of the Follicle

📆 During each cycle:

  1. Follicular phase begins (Day 1 of the cycle):
    • Several follicles in the ovaries begin to mature under the influence of follicle-stimulating hormone (FSH).
  2. One follicle becomes dominant (called the Graafian follicle):
    • This dominant follicle grows larger and prepares its egg for ovulation.
  3. Ovulation (around mid-cycle):
    • A surge of luteinizing hormone (LH) causes the dominant follicle to burst, releasing the mature egg into the fallopian tube — this is ovulation.
  4. Post-ovulation:
    • The empty follicle transforms into the corpus luteum, which secretes progesterone to prepare the uterine lining for a potential pregnancy.

🔍 Key Follicle Stages

StageDescription
Primordial follicleSmallest, most immature follicle (present from birth)
Primary follicleBegins to grow and develop in early cycle
Secondary follicleGrows further and forms fluid-filled spaces
Graafian follicleFully mature follicle ready to release an egg
Corpus luteumFormed from the empty follicle post-ovulation

Summary

FollicleA fluid-filled structure in the ovary that nurtures an egg as it matures. The dominant follicle is the one that will release an egg during ovulation.